Amegakaryocytic thrombocytopenia associated with systemic lupus erythematosus successfully treated by a high-dose prednisolone therapy.
نویسندگان
چکیده
منابع مشابه
Cell-mediated amegakaryocytic thrombocytopenia associated with systemic lupus erythematosus.
We studied a patient with a rare complication of amegakaryocytic thrombocytopenia (AMT) associated with systemic lupus erythematosus (SLE). To investigate the underlying pathogenesis of AMT, the effects of peripheral blood T cells and serum on human megakaryocyte progenitor cells were studied using in vitro coculture techniques. Mononuclear bone marrow cells (2 X 10(5) from normal donors produc...
متن کاملSuccessful treatment of amegakaryocytic thrombocytopenia with eltrombopag in a patient with systemic lupus erythematosus (SLE).
Systemic lupus erythematosus (SLE) is an inflammatory connective tissue disease mediated by a deregulated immune system and aberrant production of proinflammatory cytokines leading to multiorgan and tissue damage. Thrombocytopenia is a common complication in patients with SLE, with a prevalence that ranges from 7–30%.1-5 The 2 main mechanisms of thrombocytopenia in SLE are increased platelet de...
متن کاملThrombocytopenia in Systemic Lupus Erythematosus
The aim of the study was to examine the clinical characteristics and prognosis according to severity of thrombocytopenia and response to treatment for thrombocytopenia in patients with systemic lupus erythematosus (SLE). We retrospectively evaluated 230 SLE patients with thrombocytopenia, and reviewed their clinical data and laboratory findings. Thrombocytopenia was defined as platelet counts u...
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Bronchial Associated Lymphoid Tissue Lymphoma in Systemic Lupus Erythematosus Successfully Treated with Rituximab Eid AlQurashi1,2, Shikha Mittoo3, Zahi Touma4, Shane Shapera5, Theodore K Marras5,6 and Muhammad Sohail Anjum7* 1Department of Medicine, Division of Respirology, King Abdullah Medical City, Saudi Arabia 2Department of Medicine, Division of Respirology, University of Toronto, Toronto...
متن کاملIsolated thrombocytopenia report of a rare presentation of childhood Systemic Lupus Erythematosus
Background: Systemic lupus erythematosus (SLE) has various presentations in children. Hematologic abnormalities is common in childhood onset of SLE, however, isolated thrombocytopenia is relatively rare. Thus, we present a child with isolated thrombocytopenia as a rare presentation of SLE. Case presentation: A 12-year-old boy with chief complaints of loss of appetite, weight loss, decrease...
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ژورنال
عنوان ژورنال: Japanese Journal of Medicine
سال: 1984
ISSN: 0021-5120,1881-123X
DOI: 10.2169/internalmedicine1962.23.135